I Am Legend (2007)
How would you even start to adapt this book for the screen? George A Romero nailed the feeling with Night of the Living Dead but of all the straight adaptations this is by far the best. Will Smith takes on the role of Neville with gusto, deserted Manhattan looks great and the film even gives us a satisfying mainstream version of that ending (but make sure you watch the alternate version). Check out The Greatest Sci-Fi Movies Never Made by David Hughes for a fascinating insight into the troubled genesis of this film that ends with a rumour that Smith might be attached.
24 Lies Per Second 